The CVCT Future Trialist (CVCT-FT) fellowship, supported jointly with industry partners and also the US NHLBI, seeks to provide young fellows with the necessary skills to lead clinical trials by engaging with major principal investigators and mentor trialists as a ‘steering committee mentee’, joining the steering committee of an ongoing major clinical trial as a full member, learning about the conduct of the trial and data collection, analyses, and interpretation, and co-authoring with the trial leadership secondary trial manuscripts. The fellowship also allows for the opportunity to take part in internal scientific and operational training as applicable for the role, including being invited to the CV outcome trial review meetings of ongoing large clinical trials in the CV–metabolic–renal axis. The interactions of the CVCT-FT in the internship should be broad, interacting with the company representative—but also with the academic faculty in the trials’ oversight committees.